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BIOTECHNOLOGY

BIOTECHNOLOGY

The industrial biotechnology department deals with research on the acquisition of natural, bioactive substances targeting the microbiome of the gastrointestinal tract of horses and small animals, as well as care products for the production of which metabolites of microorganisms and eukaryotic cells are used. Tests are carried out in specialized laboratories: microbiology, molecular biology and a prototype laboratory.

The industrial biotechnology department is responsible for the development of processes and products as well as research on recipes in the field of industrial production in accordance with the growing needs of the nutraceutical market for the production of fermented ingredients. The key elements of the production of post-fermentation components are the selection and optimization of strains and the maximization of bioproduction. Post-processing includes advanced technologies ensuring high microbial survival and stability of bioactive substances.

PRODUCTS

The industrial biotechnology department successfully commercializes its products, which are dedicated to horses and small animals.


ProBIOM liquid probiotic

Probiom + is a micellar probiotic emulsion, containing a high amount of live cultures of probiotic bacteria, intended for horses suffering from digestive system ailments, including diarrhea, food allergies, reduced immunity, impaired absorption, peptic ulcer disease and for horses during intensive use. Probiom + is a micellar probiotic containing natural lactic acid bacteria, S. bulardii yeast and a complex of bioactive nucleotides, beta-glucans and vitamins that restore the natural bacterial flora, improve digestion and absorption, improve intestinal peristalsis, cleanse and regenerate the intestines.


BioCELL clinical probiotic

BioCELL PROBIOTIC is an innovative probiotic containing the highest quality live probiotic strains combined with bio-minerals, increasing immunity, restoring intestinal peristalsis and stimulating the excretion of toxic compounds from the horse’s body.
Thanks to its double formula, BioCELL PROBIOTIC effectively eliminates pathogenic bacteria and replaces them with healthy strains, restoring the natural intestinal flora. Effectively reduces the negative effects of food poisoning, pharmacological therapies and reduces the effects of stress factors.


BioCELL SENIOR clinical probiotic

Biocell Probiotic SENIOR is a specialized probiotic dedicated to older horses, containing a clinical dose of probiotic bacteria and yeast combined with prebiotic fiber and antioxidants extracted from grape seeds. The high content of specialized strains of probiotics, postbiotics, delicate fiber and antioxidants improves digestion, improves the condition of the horse, regenerates the mucosa of the digestive tract, supports the heart, prevents anemia, regulates the digestive tract and improves the appearance of hooves and hair.

– stimulates the gastrointestinal microflora

– supports the muscular system, hooves and tendons

– natural quercetin protects the body’s cells against oxidative stress and increases the elasticity of blood vessels


IZOLITOL clinical electrolytes

IZOLITOL is a clinical isotonic preparation intended for the compensation of electrolytes lost during sports training, for horses with excessive sweating, with symptoms of dehydration and as an auxiliary preparation during clinical treatment. The combination of highly available minerals with natural polyphenols and antioxidants ensures quick electrolyte balance and rapid regeneration and de-acidification of muscles after exercise.

– highly available minerals: Na +, K +, Ca2 +, Mg2 +, Fe3 + and Cr3 + enclosed in micellar capsules

– antioxidants from grape seed extract seal blood vessels and prevent platelet aggregation and deacidify muscles

– the beta-alanine and betaine complex accelerates the metabolism of lactate in the muscles, maintains adequate hydration of the body and increases physical endurance


RedMedGel

Regenerative gel with transmembrane microvesicles isolated from stem cells for small and large animals. The innovative composition improves skin regeneration processes and accelerates the scarring process. Extracellular membrane microspheres (microvesicles-LNC +) are isolated thanks to a specialized method of their separation from stem cells developed by the International Institute of Translational Medicine. RegMedGel is recommended for the treatment of abrasions and cuts, but also large wounds with a large loss of tissue.


ASECUROL

ASECUROL is a clinical protective preparation dedicated to horses treated with steroid and non-steroid drugs as well as undergoing antibiotic therapy or ulcer treatment.

ASECUROL contains alpha-bisabolol and spiroether, which have an active anti-inflammatory effect by inhibiting the secretion of pro-inflammatory and pro-allergic compounds such as histamine, serotonin and bradykinin, and additionally regulate the secretion of gastric acid.

The highly available diammonium glycyrrhizinate also positively affects the condition of the intestinal mucosa by reducing the secretion of inflammatory markers. The polysaccharides contained in the preparation, including lichenin, isolichenin, cellulose, hemicellulose and catechin tannins, have a strong coating, shielding, moisturizing and anti-inflammatory effect. The presence of cetaric acid with proven bacteriostatic activity supports the disturbed intestinal barrier by inhibiting the growth of intestinal pathogens.


PROBIOM Cat&Dog

Probiom Cat & Dog is an innovative probiotic containing the highest quality live probiotic strains and their metabolites combined with bio-minerals, increasing immunity, restoring intestinal peristalsis and stimulating the excretion of toxic compounds from the body.

Thanks to the combination of freeze-dried cultures of probiotic bacteria and yeasts and post-biotic metabolites, Probiom Cat & Dog quickly and effectively restores the physiological bacterial flora after antibiotic therapy, diarrhea and deworming. The high content of probiotic metabolites increases and improves the absorption of nutrients in the digestive tract.


HialuDrop

HialuDrop are moisturizing eye drops intended for both small and large animals.

  • moisturize the cornea
  • relieve burning, dryness and pain in the eyes
  • support the regeneration of the mucosa after ophthalmic procedures

Hyaluronic acid co-creates the tear film and is one of the elements responsible for the proper functioning of the vitreous body of the eye, soothes irritations, moisturizes the eyeball and protects the cornea from drying out. In addition, it nourishes the cornea, protects against infections, helps flush out small foreign bodies and dust from the surface of the eye and enables sharp vision.


VitalDrop

VitalDrop are regenerative eye drops designed for both small and large animals.

  • They accelerate the healing processes of the cornea
  • They contain sphingolipids and membrane microfragments (ExMV’s)
  • They modulate repair processes by regenerating damaged eye structures
  • They inhibit the pathological neovascularization of the cornea

Thanks to the high content of membrane microfragments (ExMV’s), VitalDrop permanently modulates repair processes, regenerating damaged eye structures. Membrane micro-fragments (ExMV’s) of stem cells are used for intercellular communication, are an excellent source of growth factors and provide anti-inflammatory cytokines that effectively reduce the inflammatory reaction of the eye.

Thinking about patients with damaged cornea, we have created innovative eye drops, the action of which is based on the endogenous stimulation of the patient’s stem cells


Opti Clear

Opti Clear is a care preparation that effectively removes impurities and secretions from the eye area. Thanks to the high content of low molecular weight hyaluronic acid, it soothes irritations of the conjunctiva and facilitates the natural hydration of the eyes and eyelids.

With patients with damaged cornea in mind, we have created innovative eye drops whose action is based on the endogenous stimulation of the patient’s stem cells.


Opti Care

Opti CareTM is an innovative combination of bioactive ingredients and postbiotics that provide immediate regeneration and eye protection. Postbiotics, i.e. fermentation products of probiotic bacteria, support the natural intestinal microflora, thanks to which they improve the absorption of nutrients. A balanced complex of antioxidants such as lutein and astaxanthin protects cells against oxidative stress and UV radiation. The addition of low molecular weight hyaluronic acid ensures adequate hydration of the conjunctiva, and vitamins B3 and E improve the regeneration of rhodopsin and improve blood circulation in the eye.

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Human adipose-derived mesenchymal stem cell (ASC) line

Nr kat. A2021/10/2.1

ASC cells characterized by inorganic growth while maintaining the expression of key surface markers and maintaining specific functions and structure:

Morphologically similar to fibroblasts
Adherent cells (adhere to the surface of the culture vessel and multiply in a monolayer)
Expression of the markers CD73, CD90 and CD105; lack of CD34 expression
Ability to differentiate into dipogenic, osteogenic and chondrogenic lines
The ability of immune modulation

Application:

  • As a biological model for drug research
  • High-throughput screening
  • Stem Cell Research
  • Research on new drugs in the form of ATMP therapy (Advanced Therapy Medicinal Products)

Human cells derived from a juvenile male, isolated by enzymatic technique in accordance with GMP (Good Manufacturing Practice) principles, derived from the stromal fraction (SVF).